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KMID : 0378619950120010168
Baptist Hospital Medical Journal
1995 Volume.12 No. 1 p.168 ~ p.172
A case of Immunoglobulin deficiency with increased IgM.
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Abstract
Immunoglobulin deficiency with increased IgM. as defined by World Health Organization classification of primary immunodeficiency, is characterized by normal or increased concentrations of serum IgM and, in some cases, IgD, but decreased or absent
IgG,
IgA, and IgE Patients with these disorders have a high incidence of recurrent pyogenic infections, including otitis media, pneumona, and septisemia.
We recently experienced a cass of immunoglobulin deficiency with increased IgM in a 25-year old man. He had bee suffered from recurrent pyogenic infections-pneumonia, otitis media-since about 6 months of his age. He was admitted due to pneumonia,
and
Haemophilus influenza was isolated from the sputum culture. Also chest X-ray showed bronchiectasis His serum immunoglobulin levels levealed increased concentration of IgM and decreased IgG and IgA. He was successfully treated with antibiotics,
and
now
he is being followed-up. So we present this case with the review of literature.
KEYWORD
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